JACQUES DOBOCHET



     

Jacques Dobochet


                                  -AACHAL BURANDE

              The 2017 Nobel Prize in Chemistry was awarded to Jacques Dubochet, Joachim Frank & Richard Henderson for developing cryo-electron (Cryo-EM) microscopy for the high-resolution structure determination of biomolecules in solution.
           The work essentially deals with capturing extremely high-resolution images of a biomolecules. One of the applications of the three technology will be in medicine in health.
In awarding the three the Nobel Prize in Chemistry, the Royal Swedish Academy of Sciences said that th The Cryo-EM method makes it possible to portray biomolecules in a 3D form after freezing them very fast. The method does so in a way that the biomolecules are preserved in their natural shape.
The three's work has also led to an improvement in the electron microscope's resolution. Due to their work, electron microscopes are now able to visualise proteins at atomic resolution.
            "technology h What real-implications does the Jacques Dubochet, Joachim Frank and Richard Henderson's work have? The Royal Swedish Academy of Sciences used the example of the deadly Zika virus to illustrate just how far-reaching their contrubution could be.
           "When researchers began to suspect that the Zika virus was causing the epidemic of brain-damaged newborns in Brazil, they turned to cryo-EM to visualise the virus," the academy said, adding, "Over a few months, three-dimensional (3D) images of the virus at atomic resolution were generated and researchers could start searching for potential targets for pharmaceuticals."
as taken biochemistry into a new era."

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